ALPS ETF Trust - ALPS Medical Breakthroughs ETF
US ˙ ARCA ˙ US00162Q5936

SecuritySBIO / ALPS ETF Trust - ALPS Medical Breakthroughs ETF
InstitutionMorgan Stanley
Latest Disclosed Ownership41,718 shares
Latest Disclosed Value $ 2,183,546
Morgan Stanley reports 21.44% decrease in ownership of SBIO / ALPS ETF Trust - ALPS Medical Breakthroughs ETF

On May 15, 2026 - Morgan Stanley filed a 13F-HR form disclosing ownership of 41,718 shares of ALPS ETF Trust - ALPS Medical Breakthroughs ETF (US:SBIO) valued at $2,183,520 USD as of March 31, 2026. The entity filed a previous 13F-HR/A on May 27, 2026 disclosing 53,101 shares of ALPS ETF Trust - ALPS Medical Breakthroughs ETF. This represents a change in shares of -21.44% during the quarter. The current value of the position is $2,178,514 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 41,718 -11,383 -21.44 2,184 -19.71 0.0001
2026-05-27 2025-12-31 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 53,101 4,437 9.12 2,720 43.79 0.0002
2026-02-13 2025-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 53,101 4,437 2,720 0.0002
2026-05-27 2025-09-30 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 48,664 460 0.95 1,891 30.50 0.0001
2025-11-14 2025-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 48,664 460 1,891 0.0001
2025-08-15 2025-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 48,204 -17,018 -26.09 1,450 -22.10 0.0001
2025-05-15 2025-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 65,222 -32,058 -32.95 1,860 -42.11 0.0001
2025-05-15 2024-12-31 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 97,280 8,430 9.49 3,213 -3.11 0.0002
2025-02-14 2024-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 97,280 8,430 3,213 0.0002
2025-05-14 2024-09-30 13F/A-2 ALPS ETF TR MED BREAKTHGH 00162Q593 88,850 4,061 4.79 3,317 16.47 0.0002
2025-02-14 2024-09-30 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 88,850 4,061 3,317 0.0002
2024-11-14 2024-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 88,850 4,061 3,317 0.0000
2025-05-14 2024-06-30 13F/A-2 ALPS ETF TR MED BREAKTHGH 00162Q593 84,789 -26,306 -23.68 2,847 -28.31 0.0002
2024-10-17 2024-06-30 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 84,789 -26,306 2,847 0.0002
2024-08-14 2024-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 84,789 -26,306 2,847 0.0002
2024-10-17 2024-03-31 13F/A-2 ALPS ETF TR MED BREAKTHGH 00162Q593 111,095 25,481 29.76 3,972 40.82 0.0003
2024-08-16 2024-03-31 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 111,095 25,481 3,972 0.0000
2024-05-15 2024-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 111,095 25,481 3,972 0.0003
2024-08-16 2023-12-31 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 85,614 -36,243 -29.74 2,820 -14.98 0.0002
2024-02-13 2023-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 85,614 -36,243 2,820 0.0002
2023-11-15 2023-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 121,857 -21,037 -14.72 3,317 -26.42 0.0003
2023-08-14 2023-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 142,894 28,741 25.18 4,508 45.28 0.0004
2023-05-15 2023-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 114,153 -21,033 -15.56 3,103 -24.43 0.0003
2023-02-14 2022-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 135,186 -8,667 -6.02 4,107 -5.26 0.0005
2022-11-14 2022-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 143,853 -11,460 -7.38 4,334 0.77 0.0006
2022-10-27 2022-06-30 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 155,313 -21,025 -11.92 4,301 -27.49 0.0006
2022-08-15 2022-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 155,313 -21,025 4,301 0.0001
2022-10-27 2022-03-31 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 176,338 -57,124 -24.47 5,932 -39.84 0.0008
2022-05-13 2022-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 176,338 -57,124 5,932 0.0008
2022-02-14 2021-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 233,462 -5,021 -2.11 9,861 -9.14 0.0012
2021-11-15 2021-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 238,483 6,021 2.59 10,853 -4.56 0.0015
2021-08-23 2021-06-30 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 232,462 13,441 6.14 11,372 3.29 0.0015
2021-08-16 2021-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 232,462 13,441 11,372 0.0003
2021-05-17 2021-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 219,021 10,835 5.20 11,010 3.23 0.0016
2021-02-16 2020-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 208,186 4,927 2.42 10,665 27.57 0.0016
2020-11-13 2020-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 203,259 -25,326 -11.08 8,360 -12.57 0.0016
2020-08-14 2020-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 228,585 15,819 7.43 9,562 41.76 0.0021
2020-05-26 2020-03-31 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 212,766 45,794 27.43 6,745 -4.46 0.0018
2020-05-15 2020-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 212,766 45,794 6,745 518.1566
2020-02-14 2019-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 166,972 11,789 7.60 7,060 44.14 0.0016
2019-11-14 2019-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 155,183 -81,097 -34.32 4,898 -42.61 0.0013
2019-08-14 2019-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 236,280 10,506 4.65 8,534 4.48 0.0023
2019-05-15 2019-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 225,774 41,159 22.29 8,168 57.23 0.0023
2019-02-14 2018-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 184,615 -89,605 -32.68 5,195 -51.88 0.0016
2019-04-23 2018-09-30 13F/A-2 ALPS ETF TR MED BREAKTHGH 00162Q593 274,220 120,161 78.00 10,796 88.02 0.0027
2018-11-20 2018-09-30 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 274,220 0 10,796 0.0027
2018-11-14 2018-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 274,220 120,161 10,796
2019-04-23 2018-06-30 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 154,059 33,324 27.60 5,742 38.96 0.0016
2018-08-14 2018-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 154,059 33,324 5,742
2019-04-23 2018-03-31 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 120,735 48,617 67.41 4,132 74.79 0.0011
2018-05-14 2018-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 120,735 48,617 4,132
2019-04-23 2017-12-31 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 72,118 23,146 47.26 2,364 54.81 0.0006
2018-02-14 2017-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 72,118 23,146 2,364
2017-11-14 2017-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 48,972 16,308 49.93 1,527 67.62 0.0005
2017-08-11 2017-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 32,664 6,793 26.26 911 36.58 0.0003
2017-05-22 2017-03-31 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 25,871 12,976 100.63 667 126.10 0.0002
2017-05-12 2017-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 25,871 667
2017-02-22 2016-12-31 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 12,895 -78,370 -85.87 295 -87.62 0.0001
2017-02-13 2016-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 12,895 295
2016-11-10 2016-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 91,265 11,346 14.20 2,383 31.73 0.0008
2016-08-12 2016-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 79,919 -95,193 -54.36 1,809 -52.87 0.0007
2016-05-12 2016-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 175,112 173,101 8,607.71 3,838 5,896.88 0.0015
2016-02-09 2015-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 2,011 680 51.09 64 68.42 0.0000
2016-02-08 2015-09-30 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 1,331 115 9.46 38 -13.64 0.0000
2015-11-09 2015-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 1,331 38
2015-08-12 2015-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 1,216 215 21.48 44 46.67 0.0000
2015-05-14 2015-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 1,001 1,001 30 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.