ALPS ETF Trust - ALPS Medical Breakthroughs ETF
US ˙ ARCA ˙ US00162Q5936

SecuritySBIO / ALPS ETF Trust - ALPS Medical Breakthroughs ETF
InstitutionUBS Group AG
Latest Disclosed Ownership46,189 shares
Latest Disclosed Value $ 2,417,532
UBS Group AG reports 35.08% increase in ownership of SBIO / ALPS ETF Trust - ALPS Medical Breakthroughs ETF

On May 5, 2026 - UBS Group AG filed a 13F-HR form disclosing ownership of 46,189 shares of ALPS ETF Trust - ALPS Medical Breakthroughs ETF (US:SBIO) valued at $2,417,532 USD as of March 31, 2026. The entity filed a previous 13F-HR on January 29, 2026 disclosing 34,194 shares of ALPS ETF Trust - ALPS Medical Breakthroughs ETF. This represents a change in shares of 35.08% during the quarter. The current value of the position is $2,356,563 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-05 2026-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 46,189 11,995 35.08 2,418 38.04 0.0001
2026-01-29 2025-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 34,194 581 1.73 1,751 34.07 0.0003
2025-11-13 2025-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 33,613 -19,836 -37.11 1,306 -18.73 0.0002
2025-08-14 2025-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 53,449 -1,983 -3.58 1,607 1.71 0.0003
2025-05-13 2025-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 55,432 -14,080 -20.26 1,581 -31.15 0.0003
2025-02-14 2024-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 69,512 7,918 12.86 2,296 -0.17 0.0004
2024-11-14 2024-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 61,594 -6,619 -9.70 2,299 0.39 0.0005
2024-08-14 2024-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 68,213 -20,311 -22.94 2,291 -27.62 0.0006
2024-05-13 2024-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 88,524 10,725 13.79 3,165 23.50 0.0008
2024-02-09 2023-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 77,799 -717 -0.91 2,563 19.89 0.0008
2023-11-09 2023-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 78,516 -4,464 -5.38 2,137 -18.37 0.0007
2023-08-11 2023-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 82,980 -7,668 -8.46 2,618 6.25 0.0009
2023-05-12 2023-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 90,648 -338 -0.37 2,464 -10.85 0.0009
2023-02-08 2022-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 90,986 -86,457 -48.72 2,764 -48.30 0.0010
2022-11-10 2022-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 177,443 -4,963 -2.72 5,346 5.84 0.0023
2022-08-10 2022-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 182,406 -39,164 -17.68 5,051 -32.24 0.0021
2022-05-16 2022-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 221,570 30 0.01 7,454 -20.35 0.0025
2022-02-14 2021-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 221,540 -5,496 -2.42 9,358 -9.44 0.0027
2021-11-15 2021-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 227,036 34,268 17.78 10,333 9.58 0.0033
2021-08-13 2021-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 192,768 -11,435 -5.60 9,430 -8.13 0.0030
2021-05-12 2021-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 204,203 5,759 2.90 10,265 0.97 0.0034
2021-02-11 2020-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 198,444 -2,763 -1.37 10,166 22.84 0.0034
2020-11-12 2020-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 201,207 -2,991 -1.46 8,276 -3.11 0.0031
2020-07-31 2020-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 204,198 -13,659 -6.27 8,542 23.69 0.0036
2020-05-01 2020-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 217,857 -18,833 -7.96 6,906 -30.99 0.0033
2020-02-14 2019-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 236,690 -2,261 -0.95 10,007 32.70 0.0035
2019-11-14 2019-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 238,951 -24,902 -9.44 7,541 -20.87 0.0029
2019-08-14 2019-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 263,853 3,937 1.51 9,530 1.34 0.0037
2019-05-14 2019-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 259,916 -123 -0.05 9,404 28.51 0.0039
2019-02-14 2018-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 260,039 -187,187 -41.86 7,318 -58.44 0.0033
2018-11-14 2018-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 447,226 76,161 20.52 17,607 27.31 0.0070
2018-08-14 2018-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 371,065 151,354 68.89 13,830 83.91 0.0060
2018-05-15 2018-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 219,711 41,006 22.95 7,520 28.35 0.0032
2018-02-14 2017-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 178,705 16,283 10.03 5,859 15.70 0.0024
2017-11-14 2017-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 162,422 7,180 4.63 5,064 17.09 0.0023
2017-11-14 2017-06-30 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 155,242 39,806 34.48 4,325 45.43 0.0022
2017-08-14 2017-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 155,242 4,325
2017-11-14 2017-03-31 13F/A-1 ALPS ETF TR MED BREAKTHGH 00162Q593 115,436 57,984 100.93 2,974 125.82 0.0016
2017-05-12 2017-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 115,436 2,974
2017-02-14 2016-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 57,452 26,262 84.20 1,317 61.79 0.0007
2016-11-14 2016-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 31,190 22,447 256.74 814 311.11 0.0005
2016-08-12 2016-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 8,743 3,370 62.72 198 69.23 0.0001
2016-05-12 2016-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 5,373 1,553 40.65 117 -3.31 0.0001
2016-02-16 2015-12-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 3,820 -7,970 -67.60 121 -63.22 0.0001
2015-11-13 2015-09-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 11,790 7,926 205.12 329 140.15 0.0002
2015-08-14 2015-06-30 13F ALPS ETF TR MED BREAKTHGH 00162Q593 3,864 3,036 366.67 137 448.00 0.0001
2015-05-14 2015-03-31 13F ALPS ETF TR MED BREAKTHGH 00162Q593 828 828 25 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.