Trevi Therapeutics, Inc.
US ˙ NasdaqGM ˙ US89532M1018

SecurityTRVI / Trevi Therapeutics, Inc.
InstitutionMorgan Stanley
Latest Disclosed Ownership731,255 shares
Latest Disclosed Value $ 8,723,872
Morgan Stanley reports 30.38% decrease in ownership of TRVI / Trevi Therapeutics, Inc.

On May 15, 2026 - Morgan Stanley filed a 13F-HR form disclosing ownership of 731,255 shares of Trevi Therapeutics, Inc. (US:TRVI) valued at $8,723,872 USD as of March 31, 2026. The entity filed a previous 13F-HR/A on May 27, 2026 disclosing 1,050,296 shares of Trevi Therapeutics, Inc.. This represents a change in shares of -30.38% during the quarter. The current value of the position is $10,186,382 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F TREVI THERAPEUTICS COM 89532M101 731,255 -319,041 -30.38 8,724 -33.66 0.0005
2026-05-27 2025-12-31 13F/A-1 TREVI THERAPEUTICS COM 89532M101 1,050,296 -3,251,430 -75.58 13,150 -66.59 0.0008
2026-02-13 2025-12-31 13F TREVI THERAPEUTICS COM 89532M101 1,050,296 -3,251,430 13,150 0.0008
2026-05-27 2025-09-30 13F/A-1 TREVI THERAPEUTICS COM 89532M101 4,301,726 3,277,715 320.09 39,361 602.73 0.0024
2025-11-14 2025-09-30 13F TREVI THERAPEUTICS COM 89532M101 4,301,726 3,277,715 39,361 0.0024
2025-08-15 2025-06-30 13F TREVI THERAPEUTICS COM 89532M101 1,024,011 529,444 107.05 5,601 80.10 0.0004
2025-05-15 2025-03-31 13F TREVI THERAPEUTICS COM 89532M101 494,567 303,698 159.11 3,111 295.67 0.0002
2025-05-15 2024-12-31 13F/A-1 TREVI THERAPEUTICS COM 89532M101 190,869 -7,611 -3.83 786 18.73 0.0001
2025-02-14 2024-12-31 13F TREVI THERAPEUTICS COM 89532M101 190,869 -7,611 786 0.0001
2025-05-14 2024-09-30 13F/A-2 TREVI THERAPEUTICS COM 89532M101 198,480 109,499 123.06 663 149.81 0.0000
2025-02-14 2024-09-30 13F/A-1 TREVI THERAPEUTICS COM 89532M101 198,480 109,499 663 0.0000
2024-11-14 2024-09-30 13F TREVI THERAPEUTICS COM 89532M101 198,480 109,499 663 0.0000
2025-05-14 2024-06-30 13F/A-2 TREVI THERAPEUTICS COM 89532M101 88,981 20,754 30.42 265 12.77 0.0000
2024-10-17 2024-06-30 13F/A-1 TREVI THERAPEUTICS COM 89532M101 88,981 20,754 265 0.0000
2024-08-14 2024-06-30 13F TREVI THERAPEUTICS COM 89532M101 88,981 20,754 265 0.0000
2024-10-17 2024-03-31 13F/A-2 TREVI THERAPEUTICS COM 89532M101 68,227 -80,776 -54.21 235 18.09 0.0000
2024-08-16 2024-03-31 13F/A-1 TREVI THERAPEUTICS COM 89532M101 68,227 -80,776 235 0.0000
2024-05-15 2024-03-31 13F TREVI THERAPEUTICS COM 89532M101 68,227 -80,776 235 0.0000
2024-08-16 2023-12-31 13F/A-1 TREVI THERAPEUTICS COM 89532M101 149,003 114,289 329.23 200 165.33 0.0000
2024-02-13 2023-12-31 13F TREVI THERAPEUTICS COM 89532M101 149,003 114,289 200 0.0000
2023-11-15 2023-09-30 13F TREVI THERAPEUTICS COM 89532M101 34,714 -3,077 -8.14 76 -16.67 0.0000
2023-08-14 2023-06-30 13F TREVI THERAPEUTICS COM 89532M101 37,791 37,407 9,741.41 90 0.0000
2023-05-15 2023-03-31 13F TREVI THERAPEUTICS COM 89532M101 384 -55 -12.53 1 0.0000
2023-02-14 2022-12-31 13F TREVI THERAPEUTICS COM 89532M101 439 -427,966 -99.90 1 -100.00 0.0000
2022-11-14 2022-09-30 13F TREVI THERAPEUTICS COM 89532M101 428,405 428,405 660 0.0001
2022-10-27 2022-06-30 13F/A-1 TREVI THERAPEUTICS COM 89532M101 0 -589 -100.00 0 -100.00
2022-08-15 2022-06-30 13F TREVI THERAPEUTICS COM 89532M101 0 -589 0
2022-10-27 2022-03-31 13F/A-1 TREVI THERAPEUTICS COM 89532M101 589 589 1 0.0000
2022-05-13 2022-03-31 13F TREVI THERAPEUTICS COM 89532M101 589 589 1 0.0000
2021-08-20 2021-06-30 13F/A-1 TREVI THERAPEUTICS COM 89532M101 0 -1,000 -100.00 0 -100.00
2021-08-16 2021-06-30 13F TREVI THERAPEUTICS COM 89532M101 0 -1,000 0
2021-05-17 2021-03-31 13F TREVI THERAPEUTICS COM 89532M101 1,000 1,000 3 0.0000
2020-02-14 2019-12-31 13F TREVI THERAPEUTICS COM 89532M101 0 -114 -100.00 0 -100.00
2019-11-14 2019-09-30 13F TREVI THERAPEUTICS COM 89532M101 114 -5,545 -97.99 1 -97.62 0.0000
2019-08-14 2019-06-30 13F TREVI THERAPEUTICS COM 89532M101 5,659 5,659 42 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.