Travere Therapeutics, Inc.
US ˙ NasdaqGM ˙ US89422G1076

SecurityTVTX / Travere Therapeutics, Inc.
InstitutionRenaissance Technologies Llc
ManagerJames Simons
Latest Disclosed Ownership1,966,779 shares
Latest Disclosed Value $ 58,433,004
Renaissance Technologies Llc reports 12.46% decrease in ownership of TVTX / Travere Therapeutics, Inc.

On May 14, 2026 - Renaissance Technologies Llc filed a 13F-HR form disclosing ownership of 1,966,779 shares of Travere Therapeutics, Inc. (US:TVTX) valued at $58,433,004 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 2,246,779 shares of Travere Therapeutics, Inc.. This represents a change in shares of -12.46% during the quarter. The current value of the position is $88,898,411 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F TRAVERE THERAPEUTICS COM 89422G107 1,966,779 -280,000 -12.46 58,433 -31.94 0.0914
2026-02-12 2025-12-31 13F TRAVERE THERAPEUTICS COM 89422G107 2,246,779 494,665 28.23 85,849 105.01 0.1332
2025-11-13 2025-09-30 13F TRAVERE THERAPEUTICS COM 89422G107 1,752,114 -743,000 -29.78 41,876 13.40 0.0553
2025-08-13 2025-06-30 13F TRAVERE THERAPEUTICS COM 89422G107 2,495,114 -207,700 -7.68 36,928 -23.76 0.0491
2025-05-14 2025-03-31 13F TRAVERE THERAPEUTICS COM 89422G107 2,702,814 293,300 12.17 48,434 15.39 0.0733
2025-02-13 2024-12-31 13F TRAVERE THERAPEUTICS COM 89422G107 2,409,514 534,500 28.51 41,974 60.01 0.0621
2024-11-13 2024-09-30 13F TRAVERE THERAPEUTICS COM 89422G107 1,875,014 -328,800 -14.92 26,231 44.80 0.0394
2024-08-09 2024-06-30 13F TRAVERE THERAPEUTICS COM 89422G107 2,203,814 -658,200 -23.00 18,115 82,240.91 0.0307
2024-05-13 2024-03-31 13F TRAVERE THERAPEUTICS COM 89422G107 2,862,014 -219,000 -7.11 22 -18.52 0.0347
2024-02-13 2023-12-31 13F TRAVERE THERAPEUTICS COM 89422G107 3,081,014 1,086,892 54.50 28 58.82 0.0429
2023-11-14 2023-09-30 13F TRAVERE THERAPEUTICS COM 89422G107 1,994,122 439,109 28.24 18 -26.09 0.0304
2023-08-11 2023-06-30 13F TRAVERE THERAPEUTICS COM 89422G107 1,555,013 -589,809 -27.50 24 -52.08 0.0344
2023-05-12 2023-03-31 13F TRAVERE THERAPEUTICS COM 89422G107 2,144,822 551,300 34.60 48 45.45 0.0640
2023-02-13 2022-12-31 13F TRAVERE THERAPEUTICS COM 89422G107 1,593,522 86,100 5.71 34 -99.91 0.0459
2022-11-14 2022-09-30 13F TRAVERE THERAPEUTICS COM 89422G107 1,507,422 -149,600 -9.03 37,143 -7.49 0.0525
2022-08-12 2022-06-30 13F TRAVERE THERAPEUTICS COM 89422G107 1,657,022 299,700 22.08 40,150 14.79 0.0475
2022-05-13 2022-03-31 13F TRAVERE THERAPEUTICS COM 89422G107 1,357,322 317,400 30.52 34,978 8.36 0.0410
2022-02-11 2021-12-31 13F TRAVERE THERAPEUTICS COM 89422G107 1,039,922 -200,496 -16.16 32,279 7.31 0.0402
2021-11-12 2021-09-30 13F TRAVERE THERAPEUTICS COM 89422G107 1,240,418 -470,904 -27.52 30,080 20.47 0.0388
2021-08-13 2021-06-30 13F TRAVERE THERAPEUTICS COM 89422G107 1,711,322 122,600 7.72 24,968 -37.06 0.0312
2021-05-13 2021-03-31 13F TRAVERE THERAPEUTICS COM 89422G107 1,588,722 -272,700 -14.65 39,670 -21.81 0.0494
2021-02-10 2020-12-31 13F TRAVERE THERAPEUTICS COM 89422G107 1,861,422 -95,732 -4.89 50,733 40.42 0.0551
2020-11-13 2020-09-30 13F RETROPHIN COM 761299106 1,957,154 -21,334 -1.08 36,129 -10.53 0.0361
2020-08-13 2020-06-30 13F RETROPHIN COM 761299106 1,978,488 779,700 65.04 40,381 130.88 0.0349
2020-05-14 2020-03-31 13F RETROPHIN COM 761299106 1,198,788 381,961 46.76 17,490 50.79 0.0170
2020-02-13 2019-12-31 13F RETROPHIN COM 761299106 816,827 135,902 19.96 11,599 46.97 0.0089
2019-11-13 2019-09-30 13F RETROPHIN COM 761299106 680,925 414,625 155.70 7,892 47.51 0.0067
2019-08-12 2019-06-30 13F RETROPHIN COM 761299106 266,300 132,100 98.44 5,350 76.16 0.0047
2019-05-14 2019-03-31 13F RETROPHIN COM 761299106 134,200 134,200 -49.61 3,037 -43.23 0.0028
2018-11-13 2018-09-30 13F RETROPHIN COM 761299106 0 -138,200 -100.00 0 -100.00
2018-08-13 2018-06-30 13F RETROPHIN COM 761299106 138,200 0 0.00 3,090 0.00 0.0034
2018-05-14 2018-03-31 13F RETROPHIN COM 761299106 138,200 -226,600 -62.12 3,090 -54.11 0.0034
2017-05-12 2017-03-31 13F RETROPHIN COM 761299106 364,800 323,500 783.29 6,734 761.13 0.0094
2017-02-13 2016-12-31 13F RETROPHIN COM 761299106 41,300 41,300 -88.68 782 -88.39 0.0012
2016-08-12 2016-06-30 13F RETROPHIN COM 761299106 0 -76,600 -100.00 0 -100.00
2016-05-13 2016-03-31 13F RETROPHIN COM 761299106 76,600 76,600 0.00 1,046 0.0020
2016-02-11 2015-12-31 13F RETROPHIN COM 761299106 0 -100,913 -100.00 0 -100.00
2015-11-12 2015-09-30 13F RETROPHIN COM 761299106 100,913 20,413 25.36 2,044 -23.42 0.0049
2015-08-14 2015-06-30 13F RETROPHIN COM 761299106 80,500 80,500 2,669 0.0061
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.