Travere Therapeutics, Inc.
US ˙ NasdaqGM ˙ US89422G1076

SecurityTVTX / Travere Therapeutics, Inc.
InstitutionTwo Sigma Advisers, Lp
Latest Disclosed Ownership725,500 shares
Latest Disclosed Value $ 27,721,355
Two Sigma Advisers, Lp reports 4.13% increase in ownership of TVTX / Travere Therapeutics, Inc.

On February 17, 2026 - Two Sigma Advisers, Lp filed a 13F-HR form disclosing ownership of 725,500 shares of Travere Therapeutics, Inc. (US:TVTX) valued at $27,721,355 USD as of December 31, 2025. The entity filed a previous 13F-HR on November 14, 2025 disclosing 696,700 shares of Travere Therapeutics, Inc.. This represents a change in shares of 4.13% during the quarter. The current value of the position is $32,792,600 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-02-17 2025-12-31 13F TRAVERE THERAPEUTICS COM 89422G107 725,500 28,800 4.13 27,721 66.48 0.0539
2025-11-14 2025-09-30 13F TRAVERE THERAPEUTICS COM 89422G107 696,700 -361,000 -34.13 16,651 6.38 0.0333
2025-08-14 2025-06-30 13F TRAVERE THERAPEUTICS COM 89422G107 1,057,700 12,000 1.15 15,654 -16.46 0.0321
2025-05-15 2025-03-31 13F TRAVERE THERAPEUTICS COM 89422G107 1,045,700 78,200 8.08 18,739 11.18 0.0422
2025-02-14 2024-12-31 13F TRAVERE THERAPEUTICS COM 89422G107 967,500 247,100 34.30 16,854 67.23 0.0390
2024-11-14 2024-09-30 13F TRAVERE THERAPEUTICS COM 89422G107 720,400 167,100 30.20 10,078 121.59 0.0236
2024-08-14 2024-06-30 13F TRAVERE THERAPEUTICS COM 89422G107 553,300 -146,900 -20.98 4,548 -15.75 0.0101
2024-05-15 2024-03-31 13F TRAVERE THERAPEUTICS COM 89422G107 700,200 157,400 29.00 5,399 10.64 0.0125
2024-02-14 2023-12-31 13F TRAVERE THERAPEUTICS COM 89422G107 542,800 -34,100 -5.91 4,880 -5.39 0.0114
2023-11-14 2023-09-30 13F TRAVERE THERAPEUTICS COM 89422G107 576,900 -107,900 -15.76 5,157 -50.97 0.0132
2023-08-14 2023-06-30 13F TRAVERE THERAPEUTICS COM 89422G107 684,800 -36,800 -5.10 10,519 -35.19 0.0268
2023-05-15 2023-03-31 13F TRAVERE THERAPEUTICS COM 89422G107 721,600 420,500 139.65 16,229 156.29 0.0419
2023-02-14 2022-12-31 13F TRAVERE THERAPEUTICS COM 89422G107 301,100 92,000 44.00 6,332 22.90 0.0177
2022-11-14 2022-09-30 13F TRAVERE THERAPEUTICS COM 89422G107 209,100 35,800 20.66 5,152 22.70 0.0149
2022-08-15 2022-06-30 13F TRAVERE THERAPEUTICS COM 89422G107 173,300 78,600 83.00 4,199 72.09 0.0119
2022-05-16 2022-03-31 13F TRAVERE THERAPEUTICS COM 89422G107 94,700 47,000 98.53 2,440 64.75 0.0065
2022-02-14 2021-12-31 13F TRAVERE THERAPEUTICS COM 89422G107 47,700 47,700 1,481 0.0037
2021-08-16 2021-06-30 13F TRAVERE THERAPEUTICS COM 89422G107 0 -125,900 -100.00 0 -100.00
2021-05-17 2021-03-31 13F TRAVERE THERAPEUTICS COM 89422G107 125,900 -31,700 -20.11 3,144 -26.80 0.0086
2021-02-16 2020-12-31 13F TRAVERE THERAPEUTICS COM 89422G107 157,600 -23,400 -12.93 4,295 28.55 0.0115
2020-11-16 2020-09-30 13F RETROPHIN COM 761299106 181,000 -71,500 -28.32 3,341 -35.18 0.0095
2020-09-15 2020-06-30 13F/A-1 RETROPHIN COM 761299106 252,500 -14,600 -5.47 5,154 32.26 0.0151
2020-08-14 2020-06-30 13F RETROPHIN COM 761299106 252,500 -14,600 5,154 14,893.3483
2020-05-15 2020-03-31 13F RETROPHIN COM 761299106 267,100 -141,418 -34.62 3,897 -32.82 0.0149
2020-02-14 2019-12-31 13F RETROPHIN COM 761299106 408,518 7,818 1.95 5,801 24.91 0.0135
2019-11-14 2019-09-30 13F RETROPHIN COM 761299106 400,700 166,600 71.17 4,644 -1.25 0.0114
2019-08-14 2019-06-30 13F RETROPHIN COM 761299106 234,100 27,200 13.15 4,703 0.45 0.0117
2019-05-15 2019-03-31 13F RETROPHIN COM 761299106 206,900 109,300 111.99 4,682 111.95 0.0118
2019-02-14 2018-12-31 13F RETROPHIN COM 761299106 97,600 42,100 75.86 2,209 38.50 0.0060
2018-11-14 2018-09-30 13F RETROPHIN COM 761299106 55,500 -22,900 -29.21 1,595 -25.36 0.0039
2018-08-14 2018-06-30 13F RETROPHIN COM 761299106 78,400 39,100 99.49 2,137 143.12 0.0057
2018-05-15 2018-03-31 13F RETROPHIN COM 761299106 39,300 2,600 7.08 879 13.71 0.0024
2018-02-14 2017-12-31 13F RETROPHIN COM 761299106 36,700 -34,300 -48.31 773 -56.25 0.0021
2017-11-14 2017-09-30 13F RETROPHIN COM 761299106 71,000 26,300 58.84 1,767 114.18 0.0050
2017-05-15 2017-03-31 13F RETROPHIN COM 761299106 44,700 -8,400 -15.82 825 -17.91 0.0027
2017-02-14 2016-12-31 13F RETROPHIN COM 761299106 53,100 -33,800 -38.90 1,005 -48.33 0.0038
2016-11-14 2016-09-30 13F RETROPHIN COM 761299106 86,900 39,100 81.80 1,945 128.55 0.0083
2016-08-15 2016-06-30 13F RETROPHIN COM 761299106 47,800 -3,900 -7.54 851 20.54 0.0043
2016-05-16 2016-03-31 13F RETROPHIN COM 761299106 51,700 -63,015 -54.93 706 -68.10 0.0040
2016-02-16 2015-12-31 13F RETROPHIN COM 761299106 114,715 -81,892 -41.65 2,213 -46.64 0.0132
2015-11-16 2015-09-30 13F RETROPHIN COM 761299106 196,607 189,607 2,708.67 4,147 1,687.50 0.0262
2016-02-09 2015-06-30 13F/A-1 RETROPHIN COMMON STOCK 761299106 7,000 7,000 232 0.0018
2015-08-14 2015-06-30 13F RETROPHIN COMMON STOCK 761299106 6,700 221 0.0017
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.