Twist Bioscience Corporation
US ˙ NasdaqGS ˙ US90184D1000

SecurityTWST / Twist Bioscience Corporation
InstitutionSquarepoint Ops LLC
Latest Disclosed Ownership153,526 shares
Latest Disclosed Value $ 7,295,556
Squarepoint Ops LLC reports 329.84% increase in ownership of TWST / Twist Bioscience Corporation

On May 15, 2026 - Squarepoint Ops LLC filed a 13F-HR form disclosing ownership of 153,526 shares of Twist Bioscience Corporation (US:TWST) valued at $7,295,556 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 35,717 shares of Twist Bioscience Corporation. This represents a change in shares of 329.84% during the quarter. The current value of the position is $11,104,536 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F TWIST BIOSCIENCE COM 90184D100 153,526 117,809 329.84 7,296 544.43 0.0086
2026-02-13 2025-12-31 13F TWIST BIOSCIENCE COM 90184D100 35,717 -40,080 -52.88 1,133 -46.90 0.0012
2025-11-14 2025-09-30 13F TWIST BIOSCIENCE COM 90184D100 75,797 4,089 5.70 2,133 -19.18 0.0021
2025-08-27 2025-06-30 13F/A-1 TWIST BIOSCIENCE COM 90184D100 71,708 47,221 192.84 2,638 174.51 0.0027
2025-08-14 2025-06-30 13F TWIST BIOSCIENCE COM 90184D100 71,708 47,221 2,638 0.0027
2025-08-27 2025-03-31 13F/A-1 TWIST BIOSCIENCE COM 90184D100 24,487 -3,279 -11.81 961 -25.50 0.0012
2025-05-15 2025-03-31 13F TWIST BIOSCIENCE COM 90184D100 24,487 -3,279 961 0.0012
2025-02-14 2024-12-31 13F TWIST BIOSCIENCE COM 90184D100 27,766 -245,678 -89.85 1,290 -89.56 0.0013
2024-11-14 2024-09-30 13F TWIST BIOSCIENCE COM 90184D100 273,444 262,953 2,506.46 12,354 2,294.19 0.0193
2024-08-14 2024-06-30 13F TWIST BIOSCIENCE COM 90184D100 10,491 -147,925 -93.38 517 -90.51 0.0009
2024-05-15 2024-03-31 13F TWIST BIOSCIENCE COM 90184D100 158,416 80,451 103.19 5,435 89.18 0.0094
2024-02-14 2023-12-31 13F TWIST BIOSCIENCE COM 90184D100 77,965 47,296 154.21 2,874 362.64 0.0054
2023-11-14 2023-09-30 13F TWIST BIOSCIENCE COM 90184D100 30,669 30,669 621 0.0015
2023-08-14 2023-06-30 13F TWIST BIOSCIENCE COM 90184D100 0 -134,772 -100.00 0 -100.00
2023-05-15 2023-03-31 13F TWIST BIOSCIENCE COM 90184D100 134,772 134,772 2,032 0.0083
2023-02-14 2022-12-31 13F TWIST BIOSCIENCE COM 90184D100 0 -36,488 -100.00 0 -100.00
2022-11-14 2022-09-30 13F TWIST BIOSCIENCE COM 90184D100 36,488 -21,340 -36.90 1,286 -36.40 0.0065
2022-08-15 2022-06-30 13F TWIST BIOSCIENCE COM 90184D100 57,828 10,827 23.04 2,022 -12.88 0.0112
2022-05-16 2022-03-31 13F TWIST BIOSCIENCE COM 90184D100 47,001 38,664 463.76 2,321 259.84 0.0099
2022-02-14 2021-12-31 13F TWIST BIOSCIENCE COM 90184D100 8,337 5,427 186.49 645 107.40 0.0017
2021-11-15 2021-09-30 13F TWIST BIOSCIENCE COM 90184D100 2,910 2,910 311 0.0009
2021-05-17 2021-03-31 13F TWIST BIOSCIENCE COM 90184D100 0 -1,889 -100.00 0 -100.00
2021-02-16 2020-12-31 13F TWIST BIOSCIENCE COM 90184D100 1,889 1,889 267 0.0020
2020-11-16 2020-09-30 13F TWIST BIOSCIENCE COM 90184D100 0 -7,998 -100.00 0 -100.00
2020-08-14 2020-06-30 13F TWIST BIOSCIENCE COM 90184D100 7,998 -6,434 -44.58 362 -17.91 0.0059
2020-05-15 2020-03-31 13F TWIST BIOSCIENCE COM 90184D100 14,432 -82,595 -85.13 441 -78.36 0.0113
2020-02-14 2019-12-31 13F TWIST BIOSCIENCE COM 90184D100 97,027 -9,387 -8.82 2,038 -19.80 0.0121
2019-11-14 2019-09-30 13F TWIST BIOSCIENCE COM 90184D100 106,414 31,274 41.62 2,541 16.56 0.0227
2019-08-14 2019-06-30 13F TWIST BIOSCIENCE COM 90184D100 75,140 75,140 2,180 0.0212
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.