Vanda Pharmaceuticals Inc.
US ˙ NasdaqGM ˙ US9216591084

SecurityVNDA / Vanda Pharmaceuticals Inc.
InstitutionD. E. Shaw & Co., Inc.
ManagerDE Shaw
Latest Disclosed Ownership0 shares
Latest Disclosed Value $ 0
D. E. Shaw & Co., Inc. closes position in VNDA / Vanda Pharmaceuticals Inc.

On May 15, 2026 - D. E. Shaw & Co., Inc. filed a 13F-HR form disclosing ownership of 0 shares of Vanda Pharmaceuticals Inc. (US:VNDA) valued at $0 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 18,600 shares of Vanda Pharmaceuticals Inc.. The current value of the position is $0 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

Upgrade to unlock premium data and export to Excel .

Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F VANDA PHARMACEUTICALS COM 921659108 0 -100.00 0
2026-02-17 2025-12-31 13F VANDA PHARMACEUTICALS COM 921659108 18,600 -103,727 -84.79 164 -73.11 0.0001
2025-11-14 2025-09-30 13F VANDA PHARMACEUTICALS COM 921659108 122,327 -41,817 -25.48 610 -21.19 0.0003
2025-08-14 2025-06-30 13F VANDA PHARMACEUTICALS COM 921659108 164,144 -26,221 -13.77 775 -11.34 0.0005
2025-05-15 2025-03-31 13F VANDA PHARMACEUTICALS COM 921659108 190,365 -113,781 -37.41 874 -40.04 0.0008
2025-02-14 2024-12-31 13F VANDA PHARMACEUTICALS COM 921659108 304,146 -255,652 -45.67 1,457 -44.53 0.0011
2024-11-14 2024-09-30 13F VANDA PHARMACEUTICALS COM 921659108 559,798 -132,938 -19.19 2,625 -32.92 0.0023
2024-08-14 2024-06-30 13F VANDA PHARMACEUTICALS COM 921659108 692,736 -1,110,106 -61.58 3,914 -47.19 0.0037
2024-05-15 2024-03-31 13F VANDA PHARMACEUTICALS COM 921659108 1,802,842 -309,283 -14.64 7,410 -16.87 0.0063
2024-02-14 2023-12-31 13F VANDA PHARMACEUTICALS COM 921659108 2,112,125 164,386 8.44 8,913 5.93 0.0078
2023-11-14 2023-09-30 13F VANDA PHARMACEUTICALS COM 921659108 1,947,739 666,261 51.99 8,414 -0.36 0.0088
2023-08-14 2023-06-30 13F VANDA PHARMACEUTICALS COM 921659108 1,281,478 -81,619 -5.99 8,445 -8.76 0.0086
2023-05-15 2023-03-31 13F VANDA PHARMACEUTICALS COM 921659108 1,363,097 266,662 24.32 9,255 14.23 0.0099
2023-02-14 2022-12-31 13F VANDA PHARMACEUTICALS COM 921659108 1,096,435 193,006 21.36 8,103 -9.23 0.0090
2022-11-14 2022-09-30 13F VANDA PHARMACEUTICALS COM 921659108 903,429 51,451 6.04 8,926 -3.88 0.0107
2022-08-15 2022-06-30 13F VANDA PHARMACEUTICALS COM 921659108 851,978 182,831 27.32 9,286 22.68 0.0109
2022-05-16 2022-03-31 13F VANDA PHARMACEUTICALS COM 921659108 669,147 43,087 6.88 7,569 -22.95 0.0071
2022-02-14 2021-12-31 13F VANDA PHARMACEUTICALS COM 921659108 626,060 -199,840 -24.20 9,823 -30.61 0.0081
2021-11-15 2021-09-30 13F VANDA PHARMACEUTICALS COM 921659108 825,900 -55,447 -6.29 14,156 -25.33 0.0128
2021-08-16 2021-06-30 13F VANDA PHARMACEUTICALS COM 921659108 881,347 126,918 16.82 18,958 67.30 0.0164
2021-05-17 2021-03-31 13F VANDA PHARMACEUTICALS COM 921659108 754,429 341,970 82.91 11,332 109.12 0.0109
2021-02-16 2020-12-31 13F VANDA PHARMACEUTICALS COM 921659108 412,459 -130,082 -23.98 5,419 3.40 0.0048
2020-11-16 2020-09-30 13F VANDA PHARMACEUTICALS COM 921659108 542,541 -183,363 -25.26 5,241 -36.89 0.0054
2020-08-14 2020-06-30 13F VANDA PHARMACEUTICALS COM 921659108 725,904 114,892 18.80 8,304 31.18 0.0099
2020-05-15 2020-03-31 13F VANDA PHARMACEUTICALS COM 921659108 611,012 503,119 466.31 6,330 257.63 0.0099
2020-02-14 2019-12-31 13F VANDA PHARMACEUTICALS COM 921659108 107,893 -181,070 -62.66 1,770 -53.88 0.0020
2019-11-14 2019-09-30 13F VANDA PHARMACEUTICALS COM 921659108 288,963 268,413 1,306.15 3,838 1,223.45 0.0047
2019-08-14 2019-06-30 13F VANDA PHARMACEUTICALS COM 921659108 20,550 -10,295 -33.38 290 -48.94 0.0004
2019-05-15 2019-03-31 13F VANDA PHARMACEUTICALS COM 921659108 30,845 30,845 568 0.0007
2019-02-14 2018-12-31 13F VANDA PHARMACEUTICALS COM 921659108 0 -118,872 -100.00 0 -100.00
2018-11-14 2018-09-30 13F VANDA PHARMACEUTICALS COM 921659108 118,872 -222,024 -65.13 2,728 -57.99 0.0033
2018-08-14 2018-06-30 13F VANDA PHARMACEUTICALS COM 921659108 340,896 177,621 108.79 6,494 136.06 0.0085
2018-05-15 2018-03-31 13F VANDA PHARMACEUTICALS COM 921659108 163,275 -3,117 -1.87 2,751 8.78 0.0037
2018-02-14 2017-12-31 13F VANDA PHARMACEUTICALS COM 921659108 166,392 -39,901 -19.34 2,529 -31.52 0.0035
2017-11-14 2017-09-30 13F VANDA PHARMACEUTICALS COM 921659108 206,293 -4,356 -2.07 3,693 7.54 0.0057
2017-08-14 2017-06-30 13F VANDA PHARMACEUTICALS COM 921659108 210,649 -97,463 -31.63 3,434 -20.38 0.0057
2017-05-15 2017-03-31 13F VANDA PHARMACEUTICALS COM 921659108 308,112 -25,507 -7.65 4,313 -18.96 0.0076
2017-02-14 2016-12-31 13F VANDA PHARMACEUTICALS COM 921659108 333,619 -12,436 -3.59 5,322 -7.57 0.0090
2016-11-14 2016-09-30 13F VANDA PHARMACEUTICALS COM 921659108 346,055 126,298 57.47 5,758 134.16 0.0102
2016-08-15 2016-06-30 13F VANDA PHARMACEUTICALS COM 921659108 219,757 175,245 393.70 2,459 561.02 0.0045
2016-05-16 2016-03-31 13F VANDA PHARMACEUTICALS COM 921659108 44,512 28,215 173.13 372 144.74 0.0007
2016-02-16 2015-12-31 13F VANDA PHARMACEUTICALS COM 921659108 16,297 -44,403 -73.15 152 -77.81 0.0002
2015-11-16 2015-09-30 13F VANDA PHARMACEUTICALS COM 921659108 60,700 -171,362 -73.84 685 -76.74 0.0010
2015-08-14 2015-06-30 13F VANDA PHARMACEUTICALS COM 921659108 232,062 -120,719 -34.22 2,945 -10.24 0.0044
2015-05-15 2015-03-31 13F VANDA PHARMACEUTICALS COM 921659108 352,781 -16,490 -4.47 3,281 -37.95 0.0050
2015-02-17 2014-12-31 13F VANDA PHARMACEUTICALS COM 921659108 369,271 327,783 790.07 5,288 1,126.91 0.0068
2014-11-14 2014-09-30 13F VANDA PHARMACEUTICALS COM 921659108 41,488 -118,544 -74.08 431 -83.35 0.0006
2014-08-14 2014-06-30 13F VANDA PHARMACEUTICALS COM 921659108 160,032 -60,850 -27.55 2,589 -27.86 0.0035
2014-05-15 2014-03-31 13F VANDA PHARMACEUTICALS COM 921659108 220,882 169,018 325.89 3,589 457.30 0.0051
2014-02-14 2013-12-31 13F VANDA PHARMACEUTICALS COM 921659108 51,864 51,864 644 0.0009
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.