Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionAdvisory Alpha, LLC
Latest Disclosed Ownership2,001 shares
Latest Disclosed Value $ 893,527
Advisory Alpha, LLC reports 0.65% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 14, 2026 - Advisory Alpha, LLC filed a 13F-HR form disclosing ownership of 2,001 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $893,527 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 6, 2026 disclosing 2,014 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -0.65% during the quarter. The current value of the position is $857,108 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,001 -13 -0.65 894 -2.19 0.0244
2026-02-06 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,014 162 8.75 913 20.61 0.0249
2025-11-12 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,852 151 8.88 757 0.00 0.0211
2025-08-01 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,701 187 12.35 757 3.13 0.0236
2025-05-19 2025-03-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 1,514 222 17.18 734 41.15 0.0250
2025-04-08 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 543 -749 264 0.0163
2025-01-17 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,292 117 9.96 520 -4.76 0.0185
2024-11-12 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,175 188 19.05 546 18.18 0.0194
2024-08-21 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 987 136 15.98 463 30.14 0.0182
2024-05-06 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 851 851 356 0.0146
2021-02-16 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -67 -100.00 0 -100.00
2020-11-16 2020-09-30 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 67 67 18 0.0039
2020-11-06 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 67 67 797 31,647.9446
2020-08-14 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -170 -100.00 0 -100.00
2020-04-29 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 170 0 0.00 46 18.42 0.0128
2020-02-14 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 170 89 109.88 39 192.31 0.0094
2019-11-13 2019-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 81 81 14 0.0040
2019-08-16 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -19 -100.00 0 -100.00
2019-05-13 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 19 19 3 0.0012
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.