Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionCullinan Associates Inc
Latest Disclosed Ownership51,762 shares
Latest Disclosed Value $ 23,113,803
Cullinan Associates Inc reports 0.88% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 1, 2026 - Cullinan Associates Inc filed a 13F-HR form disclosing ownership of 51,762 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $23,113,803 USD as of March 31, 2026. The entity filed a previous 13F-HR on January 30, 2026 disclosing 51,312 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 0.88% during the quarter. The current value of the position is $22,171,735 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-01 2026-03-31 13F Vertex Pharmaceutical COM 92532F100 51,762 450 0.88 23,114 -0.64 1.8694
2026-01-30 2025-12-31 13F Vertex Pharmaceutical COM 92532F100 51,312 -100 -0.19 23,263 15.54 1.5767
2025-10-27 2025-09-30 13F Vertex Pharmaceutical COM 92532F100 51,412 -600 -1.15 20,135 -13.05 1.3110
2025-07-22 2025-06-30 13F Vertex Pharmaceutical COM 92532F100 52,012 -1,100 -2.07 23,156 -10.07 1.5272
2025-04-22 2025-03-31 13F Vertex Pharmaceutical COM 92532F100 53,112 -50 -0.09 25,750 20.28 1.8203
2025-01-24 2024-12-31 13F Vertex Pharmaceutical COM 92532F100 53,162 -1,500 -2.74 21,408 -18.44 1.3742
2024-10-23 2024-09-30 13F Vertex Pharmaceutical COM 92532F100 54,662 -1,000 -1.80 26,250 0.61 1.4805
2024-07-10 2024-06-30 13F Vertex Pharmaceutical COM 92532F100 55,662 -614 -1.09 26,090 10.91 1.4762
2024-04-18 2024-03-31 13F Vertex Pharmaceutical COM 92532F100 56,276 -2,000 -3.43 23,524 -0.79 1.3192
2024-01-24 2023-12-31 13F Vertex Pharmaceutical COM 92532F100 58,276 -2,800 -4.58 23,712 11.64 1.3221
2023-10-11 2023-09-30 13F Vertex Pharmaceutical COM 92532F100 61,076 -900 -1.45 21,239 -2.62 1.2370
2023-07-14 2023-06-30 13F Vertex Pharmaceutical COM 92532F100 61,976 -2,600 -4.03 21,810 7.20 1.1988
2023-04-05 2023-03-31 13F Vertex Pharmaceutical COM 92532F100 64,576 -305 -0.47 20,346 112,927.78 1.1886
2023-01-11 2022-12-31 13F Vertex Pharmaceutical COM 92532F100 64,881 -19,400 -23.02 19 -99.93 1.0382
2022-10-19 2022-09-30 13F Vertex Pharmaceutical COM 92532F100 84,281 -4,650 -5.23 24,403 -2.62 1.5411
2022-07-08 2022-06-30 13F Vertex Pharmaceutical COM 92532F100 88,931 -9,385 -9.55 25,060 -2.33 1.5321
2022-04-21 2022-03-31 13F Vertex Pharmaceutical COM 92532F100 98,316 -594 -0.60 25,658 18.13 1.3463
2022-01-07 2021-12-31 13F Vertex Pharmaceutical COM 92532F100 98,910 -215 -0.22 21,721 20.81 1.1057
2021-10-08 2021-09-30 13F Vertex Pharmaceutical COM 92532F100 99,125 -2,610 -2.57 17,980 -12.35 0.9933
2021-07-07 2021-06-30 13F Vertex Pharmaceutical COM 92532F100 101,735 -2,700 -2.59 20,513 -8.60 1.1488
2021-04-20 2021-03-31 13F Vertex Pharmaceutical COM 92532F100 104,435 10,800 11.53 22,442 1.41 1.2914
2021-01-14 2020-12-31 13F Vertex Pharmaceutical COM 92532F100 93,635 4,925 5.55 22,130 -8.33 1.3275
2020-10-09 2020-09-30 13F Vertex Pharmaceutical COM 92532F100 88,710 -5,679 -6.02 24,140 -11.90 1.5562
2020-07-07 2020-06-30 13F Vertex Pharmaceutical COM 92532F100 94,389 1,477 1.59 27,402 23.95 1.9218
2020-04-01 2020-03-31 13F Vertex Pharmaceutical COM 92532F100 92,912 1,641 1.80 22,108 10.63 1.8074
2020-01-15 2019-12-31 13F Vertex Pharmaceutical COM 92532F100 91,271 -10,824 -10.60 19,984 15.53 1.3359
2019-10-01 2019-09-30 13F Vertex Pharmaceutical COM 92532F100 102,095 0 0.00 17,297 -7.61 1.2313
2019-07-16 2019-06-30 13F Vertex Pharmaceutical COM 92532F100 102,095 -8,378 -7.58 18,722 -7.87 1.3589
2019-04-30 2019-03-31 13F Vertex Pharmaceutical COM 92532F100 110,473 -6,800 -5.80 20,322 4.57 1.5265
2019-01-11 2018-12-31 13F Vertex Pharmaceutical COM 92532F100 117,273 5,472 4.89 19,433 -9.82 1.6048
2018-10-19 2018-09-30 13F Vertex Pharmaceutical COM 92532F100 111,801 -8,541 -7.10 21,549 5.36 1.5600
2018-07-09 2018-06-30 13F Vertex Pharmaceutical COM 92532F100 120,342 21,795 22.12 20,453 27.35 1.5649
2018-04-26 2018-03-31 13F Vertex Pharmaceutical COM 92532F100 98,547 600 0.61 16,061 9.42 1.2166
2018-01-17 2017-12-31 13F Vertex Pharmaceutical COM 92532F100 97,947 1,093 1.13 14,678 -0.33 1.0779
2017-10-16 2017-09-30 13F Vertex Pharmaceutical COM 92532F100 96,854 -12,014 -11.04 14,726 4.96 1.1341
2017-07-12 2017-06-30 13F Vertex Pharmaceutical COM 92532F100 108,868 21,743 24.96 14,030 47.27 1.0925
2017-04-17 2017-03-31 13F Vertex Pharmaceutical COM 92532F100 87,125 -38,085 -30.42 9,527 3.28 0.7767
2017-01-30 2016-12-31 13F Vertex Pharmaceutical COM 92532F100 125,210 -2,800 -2.19 9,224 -17.38 0.7856
2016-10-03 2016-09-30 13F Vertex Pharmaceutical COM 92532F100 128,010 0 0.00 11,164 1.39 0.9544
2016-07-01 2016-06-30 13F Vertex Pharmaceutical COM 92532F100 128,010 27,323 27.14 11,011 37.57 0.8951
2016-05-20 2016-03-31 13F Vertex Pharmaceutical COM 92532F100 100,687 0 0.00 8,004 -36.82 0.6837
2016-01-12 2015-12-31 13F Vertex Pharmaceutical COM 92532F100 100,687 0 0.00 12,669 20.82 1.1030
2015-10-05 2015-09-30 13F Vertex Pharmaceutical COM 92532F100 100,687 0 0.00 10,486 -15.66 0.9578
2015-07-06 2015-06-30 13F Vertex Pharmaceutical COM 92532F100 100,687 0 0.00 12,433 4.67 1.0254
2015-04-14 2015-03-31 13F Vertex Pharmaceutical COM 92532F100 100,687 100,687 11,878 0.9216
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.