Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionCwm, Llc
Latest Disclosed Ownership8,609 shares
Latest Disclosed Value $ 3,844,166
Cwm, Llc reports 17.24% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 14, 2026 - Cwm, Llc filed a 13F-HR form disclosing ownership of 8,609 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $3,844,263 USD as of March 31, 2026. The entity filed a previous 13F-HR on January 26, 2026 disclosing 7,343 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 17.24% during the quarter. The current value of the position is $3,687,579 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 8,609 1,266 17.24 3,844 128,033.33 0.0101
2026-01-26 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 7,343 1,401 23.58 3 50.00 0.0090
2025-10-15 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 5,942 -966 -13.98 2 -33.33 0.0070
2025-07-25 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,908 -776 -10.10 3 0.00 0.0108
2025-05-01 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 7,684 1,403 22.34 4 50.00 0.0149
2025-02-04 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,281 -96 -1.51 3 0.00 0.0105
2024-10-08 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,377 -37 -0.58 3 -33.33 0.0128
2024-07-10 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,414 374 6.19 3 50.00 0.0142
2024-04-05 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,040 475 8.54 3 0.00 0.0123
2024-02-01 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 5,565 190 3.53 2 100.00 0.0122
2023-10-11 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 5,375 806 17.64 2 0.00 0.0115
2023-08-03 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 4,569 341 8.07 2 0.00 0.0099
2023-05-01 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 4,228 506 13.59 1 0.00 0.0090
2023-02-01 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,722 246 7.08 1 -99.90 0.0079
2022-10-27 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,476 294 9.24 1,006 12.15 0.0080
2022-07-28 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,182 966 43.59 897 55.19 0.0069
2022-04-21 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,216 993 81.19 578 114.87 0.0041
2022-01-31 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,223 545 80.38 269 96.35 0.0019
2021-09-15 2021-06-30 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 678 0 0.00 137 0.00 0.0011
2021-07-29 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 678 0 137 0.0011
2021-09-15 2021-03-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 678 0 0.00 137 0.00 0.0011
2021-04-27 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 680 2 146 0.0013
2021-09-15 2020-12-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 678 0 0.00 137 0.00 0.0011
2021-01-27 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 629 -49 149 0.0014
2021-09-15 2020-09-30 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 678 0 0.00 137 0.00 0.0011
2020-10-19 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 389 -289 106 0.0012
2021-09-15 2020-06-30 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 678 0 0.00 137 0.00 0.0011
2020-07-22 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 359 -319 104 0.0012
2021-09-15 2020-03-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 678 0 0.00 137 0.00 0.0011
2020-04-28 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 352 -326 84 0.0013
2021-09-14 2019-12-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 678 0 0.00 137 0.00 0.0011
2020-01-27 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 906 228 198 0.0025
2021-09-14 2019-09-30 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 678 0 0.00 137 0.00 0.0011
2019-10-22 2019-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 285 -393 48 0.0007
2021-09-14 2019-06-30 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 678 0 0.00 137 0.00 0.0011
2019-07-31 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 174 -504 32 0.0005
2021-09-02 2019-03-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 678 509 301.18 137 389.29 0.0011
2019-04-22 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 161 -8 30 0.0006
2019-01-25 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 169 -5 -2.87 28 -17.65 0.0007
2018-10-29 2018-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 174 14 8.75 34 25.93 0.0009
2018-07-31 2018-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 160 -39 -19.60 27 -15.62 0.0009
2018-04-26 2018-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 199 58 41.13 32 52.38 0.0013
2018-01-16 2017-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 141 8 6.02 21 5.00 0.0009
2017-10-16 2017-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 133 41 44.57 20 66.67 0.0009
2017-07-17 2017-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 92 20 27.78 12 50.00 0.0006
2017-04-17 2017-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 72 -39 -35.14 8 0.00 0.0005
2017-01-19 2016-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 111 109 5,450.00 8 0.0005
2016-10-17 2016-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2 0 0.00 0 0.0000
2016-07-21 2016-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2 2 0.00 0 0.0000
2016-04-18 2016-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 0 0 0.0000
2016-02-01 2015-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -128 -100.00 0 -100.00
2015-10-30 2015-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 128 128 13 0.0013
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.