Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionIntrust Bank Na
Latest Disclosed Ownership3,902 shares
Latest Disclosed Value $ 1,742,398
Intrust Bank Na reports 12.35% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 6, 2026 - Intrust Bank Na filed a 13F-HR form disclosing ownership of 3,902 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $1,742,399 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 6, 2026 disclosing 3,473 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 12.35% during the quarter. The current value of the position is $1,671,383 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-06 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,902 429 12.35 1,742 10.67 0.1420
2026-02-06 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,473 211 6.47 1,575 23.26 0.1304
2025-11-10 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,262 -541 -14.23 1,278 -24.57 0.1063
2025-08-11 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,803 197 5.46 1,693 -3.15 0.1501
2025-05-09 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,606 231 6.84 1,748 28.62 0.1729
2025-02-12 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,375 4 0.12 1,359 -13.27 0.1378
2024-11-12 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,371 14 0.42 1,568 -0.38 0.1568
2024-08-08 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,357 -55 -1.61 1,573 10.31 0.1673
2024-05-09 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,412 62 1.85 1,426 4.62 0.1528
2024-02-05 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,350 309 10.16 1,363 28.95 0.1581
2023-11-13 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,041 29 0.96 1,057 -0.19 0.1348
2023-08-10 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,012 115 3.97 1,060 16.12 0.1285
2023-05-04 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,897 321 12.46 913 22.75 0.1169
2023-02-10 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,576 205 8.65 744 8.31 0.1032
2022-11-09 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,371 202 9.31 686 12.27 0.1057
2022-08-16 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,169 450 26.18 611 36.38 0.0883
2022-05-10 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,719 798 86.64 448 121.78 0.0384
2022-05-10 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,695 442
2022-02-03 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 921 921 202 0.0243
2021-11-04 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -1,324 -100.00 0 -100.00
2021-08-05 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,324 120 9.97 267 3.49 0.0360
2021-06-02 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,204 -69 -5.42 258 -14.29 0.0371
2021-02-10 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,273 488 62.17 301 40.65 0.0456
2020-11-05 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 785 785 214 0.0380
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.