Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionMackenzie Financial Corp
Latest Disclosed Ownership96,709 shares
Latest Disclosed Value $ 43,184,437
Mackenzie Financial Corp reports 52.78% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 13, 2026 - Mackenzie Financial Corp filed a 13F-HR form disclosing ownership of 96,709 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $43,184,437 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 18, 2026 disclosing 63,299 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 52.78% during the quarter. The current value of the position is $41,424,333 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-13 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 96,709 33,410 52.78 43,184 50.66 0.0518
2026-02-18 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 63,299 8,956 16.48 28,665 34.69 0.0339
2025-11-13 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 54,343 18,068 49.81 21,283 31.79 0.0258
2025-08-13 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 36,275 209 0.58 16,150 -7.64 0.0209
2025-05-07 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 36,066 -9,566 -20.96 17,486 -4.85 0.0249
2025-05-02 2024-12-31 13F/A-2 VERTEX PHARMACEUTICALS COM 92532F100 45,632 -23,060 -33.57 18,376 -42.48 0.0250
2025-02-20 2024-12-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 45,632 -23,060 18,376 0.0239
2025-02-14 2024-12-31 13F Vertex Pharmaceuticals Common Stock 92532F100 45,632 -23,060 18,088 0.0260
2024-11-13 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 68,692 -15,942 -18.84 31,947 -19.47 0.0445
2024-08-14 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 84,634 -7,818 -8.46 39,670 2.65 0.0589
2024-05-10 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 92,452 5,625 6.48 38,646 9.39 0.0557
2024-01-30 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 86,827 3,856 4.65 35,329 23.37 0.0533
2023-10-25 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 82,971 -9,719 -10.49 28,637 -11.11 0.0481
2023-08-03 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 92,690 -118,393 -56.09 32,216 -51.56 0.0489
2023-04-24 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 211,083 102,181 93.83 66,506 111.48 0.1027
2023-02-14 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 108,902 -9,220 -7.81 31,449 -8.05 0.0525
2022-10-07 2022-09-30 13F Vertex Pharmaceuticals Common Stock 92532F100 118,122 28,080 31.19 34,201 34.79 0.0588
2022-08-10 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 90,042 -9,283 -9.35 25,373 -2.11 0.0406
2022-05-13 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 99,325 11,876 13.58 25,921 34.98 0.0348
2022-02-14 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 87,449 1,896 2.22 19,204 23.75 0.0259
2021-11-08 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 85,553 4,503 5.56 15,518 -5.04 0.0220
2021-08-11 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 81,050 10,827 15.42 16,342 8.30 0.0227
2021-05-14 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 70,223 32,402 85.67 15,090 68.81 0.0230
2021-02-10 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 37,821 13,435 55.09 8,939 34.70 0.0193
2020-11-13 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 24,386 7,080 40.91 6,636 32.09 0.0165
2020-08-13 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 17,306 7,852 83.05 5,024 123.29 0.0134
2020-05-14 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 9,454 5,281 126.55 2,250 146.17 0.0072
2020-02-13 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 4,173 2,666 176.91 914 258.43 0.0022
2019-11-14 2019-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,507 9 0.60 255 -7.27 0.0007
2019-08-23 2019-06-30 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 1,498 -29,512 -95.17 275 -95.18 0.0007
2019-08-14 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,498 -29,512 275
2019-05-15 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 31,010 -39,700 -56.14 5,704 -51.32 0.0138
2019-02-06 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 70,710 65,561 1,273.28 11,717 1,081.15 0.0308
2018-11-15 2018-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 5,149 143 2.86 992 16.57 0.0024
2018-08-13 2018-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 5,006 991 24.68 851 30.12 0.0022
2018-05-14 2018-03-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 4,015 1,775 79.24 654 94.64 0.0017
2018-05-14 2018-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 4,015 654
2018-02-13 2017-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,240 2,240 336 0.0008
2017-02-14 2016-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -13,697 -100.00 0 -100.00
2016-11-15 2016-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 13,697 -108,410 -88.78 1,195 -88.62 0.0075
2016-08-12 2016-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 122,107 6,156 5.31 10,504 13.96 0.0593
2016-05-12 2016-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 115,951 42,683 58.26 9,217 -0.02 0.0836
2016-02-12 2015-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 73,268 5,300 7.80 9,219 30.25 0.0572
2015-11-13 2015-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 67,968 64,768 2,024.00 7,078 1,691.90 0.0429
2015-08-13 2015-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,200 -1,200 -27.27 395 -23.89 0.0021
2015-05-13 2015-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 4,400 600 15.79 519 15.08 0.0027
2015-02-11 2014-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,800 -6,600 -63.46 451 -61.39 0.0023
2014-11-12 2014-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 10,400 10,400 1,168 0.0059
2013-11-12 2013-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -15,300 -100.00 0 -100.00
2013-08-20 2013-06-30 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 15,300 15,300 1,225 0.0058
2013-08-09 2013-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 15,300 1,225 0.0059
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.