Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionQuantinno Capital Management LP
Latest Disclosed Ownership126,604 shares
Latest Disclosed Value $ 56,533,833
Quantinno Capital Management LP reports 37.19% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 15, 2026 - Quantinno Capital Management LP filed a 13F-HR form disclosing ownership of 126,604 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $56,533,750 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 92,284 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 37.19% during the quarter. The current value of the position is $54,229,557 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 126,604 34,320 37.19 56,534 35.12 0.0943
2026-02-17 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 92,284 36,643 65.86 41,838 92.00 0.0840
2025-11-14 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 55,641 9,319 20.12 21,791 5.67 0.0594
2025-08-14 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 46,322 7,897 20.55 20,623 10.70 0.0891
2025-05-12 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 38,425 14,349 59.60 18,629 92.15 0.1213
2025-02-14 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 24,076 4,381 22.24 9,695 5.85 0.0953
2024-11-14 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 19,695 5,238 36.23 9,160 35.17 0.1191
2024-08-14 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 14,457 1,692 13.25 6,776 26.99 0.1219
2024-05-14 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 12,765 1,896 17.44 5,336 20.67 0.1160
2024-02-14 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 10,869 1,494 15.94 4,422 35.64 0.1548
2023-11-14 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 9,375 1,804 23.83 3,260 22.37 0.1484
2023-08-04 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,571 3,754 98.35 2,664 121.45 0.1522
2023-05-03 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,817 -164 -4.12 1,203 4.61 0.0796
2023-02-13 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,981 2,573 182.74 1,150 181.86 0.0858
2022-11-08 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,408 250 21.59 408 25.15 0.0525
2022-08-15 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,158 1,158 326 0.0470
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.