Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionScotia Capital Inc.
Latest Disclosed Ownership4,861 shares
Latest Disclosed Value $ 2,170,670
Scotia Capital Inc. reports 5.89% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 13, 2026 - Scotia Capital Inc. filed a 13F-HR form disclosing ownership of 4,861 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $2,170,631 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 5,165 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -5.89% during the quarter. The current value of the position is $2,082,161 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-13 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 4,861 -304 -5.89 2,171 -7.26 0.0089
2026-02-12 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 5,165 -756 -12.77 2,341 0.91 0.0094
2025-11-14 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 5,921 -563 -8.68 2,319 -19.65 0.0099
2025-08-13 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,484 412 6.79 2,886 -1.94 0.0136
2025-05-09 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,072 -695 -10.27 2,944 8.00 0.0158
2025-02-13 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,767 -573 -7.81 2,726 -20.16 0.0144
2024-11-13 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,340 -458 -5.87 3,414 -6.60 0.0183
2024-08-14 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,798 297 3.96 3,655 16.56 0.0214
2024-05-14 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 7,501 222 3.05 3,135 5.88 0.0187
2024-02-12 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 7,279 -638 -8.06 2,961 7.56 0.0191
2023-11-14 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,917 -617 -7.23 2,754 -8.33 0.0199
2023-08-03 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 8,534 371 4.54 3,003 16.76 0.0206
2023-05-11 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 8,163 -71 -0.86 2,573 8.16 0.0188
2023-02-09 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 8,234 135 1.67 2,379 1.41 0.0183
2022-11-10 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 8,099 -7,788 -49.02 2,345 -47.62 0.0190
2022-08-05 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 15,887 -4,099 -20.51 4,477 -14.17 0.0333
2022-05-09 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 19,986 -3,497 -14.89 5,216 1.16 0.0330
2022-02-11 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 23,483 7,458 46.54 5,156 77.36 0.0338
2021-11-12 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 16,025 -16,189 -50.25 2,907 -55.25 0.0212
2021-08-12 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 32,214 180 0.56 6,496 -5.62 0.0475
2021-05-06 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 32,034 14,750 85.34 6,883 68.49 0.0558
2021-02-11 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 17,284 4,055 30.65 4,085 13.47 0.0375
2020-11-12 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 13,229 -2,141 -13.93 3,600 -20.28 0.0390
2020-08-11 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 15,370 -521 -3.28 4,516 19.44 0.0632
2020-05-15 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 15,891 -1,201 -7.03 3,781 0.93 0.0527
2020-02-13 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 17,092 120 0.71 3,746 30.30 0.0416
2019-11-14 2019-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 16,972 -769 -4.33 2,875 -11.67 0.0339
2019-08-13 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 17,741 590 3.44 3,255 3.27 0.0397
2019-05-15 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 17,151 -75 -0.44 3,152 10.44 0.0406
2019-02-11 2018-12-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 17,226 438 2.61 2,854 -11.80 0.0422
2019-02-11 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 16,788 3,236
2018-11-14 2018-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 16,788 -1,203 -6.69 3,236 11.36 0.0410
2018-08-13 2018-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 17,991 0 0.00 2,906 -0.85 0.0405
2018-05-15 2018-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 17,991 575 3.30 2,931 12.30 0.0404
2018-02-13 2017-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 17,416 615 3.66 2,610 2.19 0.0348
2017-11-14 2017-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 16,801 -169 -1.00 2,554 16.78 0.0364
2017-08-15 2017-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 16,970 -1,795 -9.57 2,187 6.42 0.0369
2017-05-15 2017-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 18,765 -542 -2.81 2,055 44.31 0.0351
2017-02-14 2016-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 19,307 -3,814 -16.50 1,424 -29.37 0.0227
2016-11-14 2016-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 23,121 13,290 135.18 2,016 137.74 0.0370
2016-08-11 2016-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 9,831 290 3.04 848 11.73 0.0172
2016-05-12 2016-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 9,541 6,766 243.82 759 117.48 0.0166
2016-02-11 2015-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,775 0 0.00 349 20.34 0.0079
2015-11-13 2015-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,775 170 6.53 290 -7.94 0.0066
2015-08-13 2015-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,605 -243,574 -98.94 315 -98.28 0.0063
2014-02-14 2013-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 246,179 -32,250 -11.58 18,288 -13.36 0.4361
2013-11-14 2013-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 278,429 32,950 13.42 21,108 7.64 0.5655
2013-08-13 2013-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 245,479 245,479 19,609 0.7570
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.