Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionWedbush Securities Inc
Latest Disclosed Ownership5,417 shares
Latest Disclosed Value $ 2,419
Wedbush Securities Inc reports 2.59% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On April 21, 2026 - Wedbush Securities Inc filed a 13F-HR form disclosing ownership of 5,417 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $2,418,907 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 5,561 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -2.59% during the quarter. The current value of the position is $2,392,906 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-04-21 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 5,417 -144 -2.59 2 0.00 0.0705
2026-02-12 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 5,561 -589 -9.58 3 0.00 0.0736
2025-11-06 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,150 -472 -7.13 2 0.00 0.0787
2025-08-06 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,622 19 0.29 3 -33.33 0.1030
2025-05-06 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,603 317 5.04 3 50.00 0.1175
2025-02-13 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,286 -58 -0.91 3 0.00 0.0902
2024-11-08 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,344 -247 -3.75 3 -33.33 0.1094
2024-08-07 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,591 381 6.14 3 50.00 0.1104
2024-05-15 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,210 290 4.90 3 0.00 0.0968
2024-02-12 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 5,920 1,258 26.98 2 100.00 0.1067
2023-11-14 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 4,662 503 12.09 2 0.00 0.0806
2023-08-14 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 4,159 -740 -15.11 1 0.00 0.0698
2023-05-09 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 4,899 99 2.06 2 0.00 0.0773
2023-01-31 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 4,800 127 2.72 1 -99.93 0.0762
2022-10-18 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 4,673 423 9.95 1,353 12.94 0.0760
2022-07-21 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 4,250 -1,272 -23.04 1,198 -16.86 0.0652
2022-04-19 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 5,522 -165 -2.90 1,441 15.37 0.0659
2022-01-13 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 5,687 -2,428 -29.92 1,249 -15.15 0.0538
2021-10-08 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 8,115 46 0.57 1,472 -9.53 0.0699
2021-07-27 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 8,069 1,101 15.80 1,627 8.68 0.0769
2021-04-26 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,968 396 6.03 1,497 -3.61 0.0829
2021-02-16 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,572 -118 -1.76 1,553 -14.67 0.1362
2020-10-20 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,690 -2,697 -28.73 1,820 -33.21 0.1745
2020-07-16 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 9,387 149 1.61 2,725 23.98 0.2577
2020-04-17 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 9,238 -58 -0.62 2,198 8.01 0.2616
2020-01-16 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 9,296 -30 -0.32 2,035 28.80 0.1809
2019-10-17 2019-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 9,326 207 2.27 1,580 -5.50 0.1546
2019-08-01 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 9,119 -97 -1.05 1,672 -1.36 0.1681
2019-04-17 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 9,216 -208 -2.21 1,695 8.51 0.1821
2019-01-31 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 9,424 -166 -1.73 1,562 -15.48 0.1996
2018-11-13 2018-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 9,590 145 1.54 1,848 15.14 0.2097
2018-08-03 2018-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 9,445 -977 -9.37 1,605 -5.53 0.1990
2018-05-01 2018-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 10,422 215 2.11 1,699 11.05 0.2219
2018-02-09 2017-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 10,207 2,154 26.75 1,530 25.00 0.1869
2017-10-31 2017-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 8,053 -11 -0.14 1,224 17.81 0.1590
2017-08-02 2017-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 8,064 8,064 1,039 0.1348
2017-05-05 2017-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -4,238 -100.00 0 -100.00
2017-01-25 2016-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 4,238 -3,456 -44.92 312 -53.50 0.0459
2016-11-04 2016-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,694 7,694 671 0.0999
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.