Xeris Biopharma Holdings, Inc.
US ˙ NasdaqGS ˙ US98422E1038

SecurityXERS / Xeris Biopharma Holdings, Inc.
InstitutionSquarepoint Ops LLC
Latest Disclosed Ownership614,550 shares
Latest Disclosed Value $ 3,564,390
Squarepoint Ops LLC reports 27.28% increase in ownership of XERS / Xeris Biopharma Holdings, Inc.

On May 15, 2026 - Squarepoint Ops LLC filed a 13F-HR form disclosing ownership of 614,550 shares of Xeris Biopharma Holdings, Inc. (US:XERS) valued at $3,564,390 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 482,832 shares of Xeris Biopharma Holdings, Inc.. This represents a change in shares of 27.28% during the quarter. The current value of the position is $3,619,700 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F XERIS BIOPHARMA HOLDINGS COM 98422E103 614,550 131,718 27.28 3,564 -5.96 0.0042
2026-02-13 2025-12-31 13F XERIS BIOPHARMA HOLDINGS COM 98422E103 482,832 -196,249 -28.90 3,790 -31.43 0.0040
2025-11-14 2025-09-30 13F XERIS BIOPHARMA HOLDINGS COM 98422E103 679,081 394,514 138.64 5,528 316.19 0.0056
2025-08-27 2025-06-30 13F/A-1 XERIS BIOPHARMA HOLDINGS COM 98422E103 284,567 268,572 1,679.10 1,329 1,426.44 0.0014
2025-08-14 2025-06-30 13F XERIS BIOPHARMA HOLDINGS COM 98422E103 284,567 268,572 1,329 0.0014
2025-08-27 2025-03-31 13F/A-1 XERIS BIOPHARMA HOLDINGS COM 98422E103 15,995 -24,774 -60.77 88 -36.96 0.0001
2025-05-15 2025-03-31 13F XERIS BIOPHARMA HOLDINGS COM 98422E103 15,995 -24,774 88 0.0001
2025-02-14 2024-12-31 13F XERIS BIOPHARMA HOLDINGS COM 98422E103 40,769 22,084 118.19 138 160.38 0.0001
2024-11-14 2024-09-30 13F XERIS BIOPHARMA HOLDINGS COM 98422E103 18,685 18,685 53 0.0001
2022-11-14 2022-09-30 13F XERIS BIOPHARMA HOLDINGS COM 98422E103 0 -11,651 -100.00 0 -100.00
2022-08-15 2022-06-30 13F XERIS BIOPHARMA HOLDINGS COM 98422E103 11,651 -121,799 -91.27 18 -94.74 0.0001
2022-05-16 2022-03-31 13F XERIS BIOPHARMA HOLDINGS COM 98422E103 133,450 119,567 861.25 342 734.15 0.0015
2022-02-14 2021-12-31 13F XERIS BIOPHARMA HOLDINGS COM 98422E103 13,883 13,883 41 0.0001
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.